- Pfizer (NYSE: PFE) completes $7 Billion acquisition of Metsera (NASD: MTSR), adds MET-097i, MET-233i, and Expands Clinical Obesity Pipeline in Strategic Move for Cardiometabolic Therapeutics Leadership: The acquisition of Metsera brings new advanced obesity and cardiometabolic drug candidates, including injectable and oral therapies, accelerating innovation in this high-growth field. The deal enables rapid research, expanded expertise, and improved access to cutting-edge treatments, driven by milestone-based investments and integration of Metsera’s scientific strengths. (Link)
- Day One Biopharmaceuticals (NASD: DAWN) to acquire Mersana Therapeutics (NASD: MRSN) in $285 Million Deal to Advance Novel ADC Emiltatug Ledadotin for Adenoid Cystic Carcinoma and expanded Oncology Portfolio: Emiltatug ledadotin (Emi-Le) targets B7-H4 in adenoid cystic carcinoma, showing promising early anti-tumour activity for patients lacking effective therapies. Day One’s acquisition plan supports rapid clinical progress, with milestones tied to regulatory and commercial outcomes, aiming to advance this innovative cancer treatment for diverse, underserved populations. (Link)
- Galecto (NASD: GLTO) acquires Damora Therapeutics, With $285M Investment Led by Fairmount, Viking Global, Venrock, Wellington, RA Capital, Andreessen Horowitz, and Others to Advance Anti-mutCALR Therapies for Blood Cancers: The merger advances pioneering treatments for rare blood cancers, with lead antibody DMR-001 designed for greater potency and patient convenience. Expanded research and strategic guidance support rapid clinical progress, including novel therapies for acute myeloid leukaemia, improved trial designs, and broader access for affected patients. (Link)
- Fabric acquires UCM Digital Health, adding 400 Payer and Employer Clients, to expand AI-Powered Virtual Care Nationwide: The acquisition expands Fabric’s reach, offering AI-powered virtual care for over one million new lives and enhancing efficiency for patients, payers, and providers. By integrating UCM’s clinical expertise, Fabric improves seamless care delivery, cost savings, and access, strengthening its network across health systems and employer partnerships nationwide. (Link)
- Luma Health acquires Tonic Health from R1, Expanding Patient Intake and Follow-Up Solutions for Over 1,000 Health Systems and 100 Million Patients, for EHR-Integrated Care Innovation: The integration empowers healthcare organizations with advanced digital tools for automating patient intake, consent, and follow-up. By reducing manual tasks and streamlining data coordination, clinical teams benefit from improved workflow efficiency and better patient communication. Enhanced electronic health record connectivity ensures patients experience smoother journeys and greater access to personalized care. (Link)
- Emergence, backed by The Pritzker Organization, acquires MedEvolve, to Transform AI-Driven Revenue Cycle Management for Healthcare Providers: MedEvolve will accelerate development of advanced automation and analytics tools to help healthcare organizations address operational inefficiencies and financial pressures. Its platform offers real-time insights for process improvement and margin recovery, supporting increased transparency, effective collections, and sustainable performance management in complex revenue cycle operations. (Link)
- Get Well and RhythmX AI Combine Under SymphonyAI Group, to Form GW RhythmX and Advance Precision Care AI for 150 Health Systems and 85 Million Patients: The combined entity delivers integrated engagement and precision care using AI-driven data insights, streamlining patient support and clinical workflow for providers. Its enterprise-scale approach offers tailored recommendations, improved outcomes, and operational efficiency, with demonstrated success in enhancing care quality, readmission rates, and patient satisfaction across diverse healthcare settings. (Link)
- Diversis Capital Unites Genesis Automation Healthcare, Kermit, and Meperia to Launch First End-to-End Clinical Supply Chain Platform and Highlight $1B in Global Annual Savings for 100+ Hospitals and Health Networks: The Genesis platform streamlines hospital and ambulatory center supply chains with unified digital management for inventory, charge capture, and contract pricing. Automated workflows and analytics improve data quality, reduce waste, and strengthen compliance, enabling clinicians to prioritize patient care while finance teams achieve greater transparency and control over spending. (Link)
- Vituity Integrates Focus Medical Imaging, Expands Physician-Led Model Into Diagnostic and Interventional Radiology for Hospitals and Health Systems Nationwide: The partnership enhances clinical services with a physician-led approach, empowering medical professionals in decision-making and governance. Expanded diagnostic and interventional radiology offerings, combined with innovative teleradiology, improve operational efficiency and patient care. Hospitals and imaging centers gain more coordinated, effective, and sustainable service delivery across the healthcare continuum. (Link)
- OneOncology and Cancer Specialists of North Florida (CSNF) Forge Partnership, via its financial sponsor TPG, to Elevate Community-Based Cancer Care and Expand Integrated Oncology Services Across North Florida: The collaboration improves oncology care for thousands of patients with access to advanced diagnostics, accelerated clinical research, and streamlined treatment delivery. Patients benefit from reduced wait times, comprehensive support, and integrated technology resources, while clinicians retain independence and expand expertise. The alliance promotes regional access to innovative therapies and superior care coordination. (Link)
- Hyve acquires Health Grown Advisory Network (HGAN), Strengthening Healthcare Innovation Partnerships and Behavioural Health Tech Integration: The integration provides ongoing support and tailored connections for digital health innovators and organizations, enhancing marketing, strategy, and system navigation. Expanded advisory resources deepen collaboration, foster scalable partnerships, and enable health industry leaders to engage beyond traditional event cycles, increasing opportunities for impactful innovation and consumer health benefits. (Link)
- The Lockwood Group acquires Research To Practice (RTP), via its financial sponsor Ares Management, expanding Global Oncology Education: The partnership enhances global oncology education by combining proven training formats with advanced consulting and communication expertise. Oncology professionals gain access to innovative, evidence-based resources reflecting current clinical advances. This collaboration delivers practical knowledge, supports professional growth, and helps clinicians make informed decisions to improve patient outcomes worldwide. (Link)
News Healthcare Deals, Investments & Update Week ending Oct 27th 2025
1. Hologic (NASD: HOLX) to go private in $18.3 Billion acquisition by Blackstone and TPG, Minority Stakes for Abu Dhabi Investment Authority and GIC The transaction is designed to deliver compelling value to shareholders and highlights continued innovation in women’s health and AI-driven diagnostics. Hologic will maintain its brand and headquarters while operating privately. The agreement includes a 45-day “go-shop” period, and closing remains subject to regulatory and shareholder approvals, with completion anticipated in the first half of 2026. (Link)
2. Novartis (NYSE: NVS) to acquire Avidity Biosciences (NASD: RNA) for $12 Billion; SpinCo to Emerge as Independent Cardiology-Focused Company The deal, unanimously approved by both boards, will give Novartis global rights to innovative RNA-based neuromuscular therapies and boost its neuroscience pipeline with potential first-in-class candidates. Avidity shareholders will receive additional SpinCo stock or cash linked to its cardiology assets. Regulatory and shareholder approvals are pending. (Link)
3. Eli Lilly (NYSE: LLY) to acquire Adverum Biotechnologies (NASD: ADVM) in Deal Centered on Ixo-vec Gene Therapy Lilly’s purchase will help advance Ixo-vec, a novel gene therapy for vision loss, offering shareholders potential milestone payments based on regulatory and sales goals. This late-stage treatment addresses a major unmet need for wet age-related macular degeneration. The acquisition also secures short-term funding for Adverum’s clinical progress. (Link)
4. Alkermes (NASD: ALKS) to acquire Avadel Pharmaceuticals (NASD: AVDL) for Up to $2.1 Billion, Expanding Sleep Medicine Portfolio with LUMRYZ™ Alkermes’ acquisition adds the FDA-approved LUMRYZ™, a once-at-bedtime sodium oxybate treatment for narcolepsy symptoms like cataplexy and excessive daytime sleepiness. The deal offers shareholders $18.50 upfront plus $1.50 contingent on FDA label expansion, a 38% premium over recent prices. Closing is expected in Q1 2026, enhancing Alkermes’ sleep medicine portfolio and leveraging Avadel’s expertise for future pipeline development. (Link)
5. DocGo (NASD: DCGO) acquires SteadyMD to Expand Telehealth Services Nationwide; SteadyMD Co-Founders Join Leadership Team DocGo acquired SteadyMD to expand its telehealth reach across all 50 states, integrating SteadyMD’s virtual clinician network with its mobile healthcare services. SteadyMD, expected to generate $25 million in 2025, serves over 3 million patients, including Fortune 10 clients. SteadyMD’s leadership joins DocGo’s team, and the acquisition is funded by DocGo’s cash reserves. (Link)
6. Lemonaid Health acquired by Bambu Ventures to relaunch as Independent Telemedicine Platform after Bankruptcy Lemonaid Health, after bankruptcy will pursue aggressive growth as an independent telemedicine and pharmacy platform. Bambu and Innova Partners provide executive leadership, focusing on affordable care, same-day prescriptions, and market expansion. Key board appointments and new investors support innovation and differentiation. (Link)
7. Opyn Health, Inc. acquires Empara to Integrate AI-Driven Benefits Engagement and Boost Platform for Self-Insured Healthcare Combining Opyn’s price transparency and virtual care expertise with Empara’s AI-powered app streamlines benefits administration and cost management for members and administrators. Empara’s founders join Opyn, and the unified platform will serve TPAs, brokers, and self-insured employers—aiming to replace legacy systems with a seamless digital access point for healthcare. (Link)
8. Oasis Health Partners® acquires PreferCare to Strengthen Value-Based, Preventive Primary Care for Seniors in North Carolina PreferCare enhances Oasis’s capabilities with in-home and virtual care for seniors, leveraging new tools, analytics, and clinical support. The partnership improves coordinated care, preventive screenings, and early interventions. By empowering physicians and supporting practices, Oasis advances health equity and outcomes, building healthier communities through a value-based care model. (Link)
9. Duly Health and Care acquire Woodridge Clinic, via its financial sponsors Ares Private Equity Group, Guidon Partners and Athyrium Capital Management, expanding Physician-led Primary Care Services across Chicagoland Woodridge Clinic, founded in 1986, excels in primary care, diabetes management, and occupational therapy. Joining Duly gives its team access to new resources and technology, expanding specialty care and services in Lemont, Lombard, and Woodridge. This partnership strengthens coordinated, patient-focused care for local families and supports ongoing provider recruitment. (Link)
10. Frontline Healthcare Partners acquires Integracare Inc. to drive expansion of Private-Pay Home Care across Ontario, Canada Integracare will benefit from expanded operational resources and Frontline’s healthcare investment expertise to reach new communities. The partnership preserves its focus on personalized, quality home care and workplace excellence, supporting growth beyond Toronto, Mississauga, and Ottawa. This move helps advance Integracare’s mission and expands personalized home health solutions across Ontario. (Link)
11. Cerebral raises $25 Million in Latest Funding Round, Accelerating Growth and Platform Integration The capital infusion, following the Resilience Lab acquisition, will support Cerebral’s nationwide expansion, platform integration, and quality initiatives like improved clinical training. Funds will enhance telehealth services, solidify insurance partnerships, and drive innovation in therapy, psychiatry, and medication management, as the company rebuilds after leadership and regulatory challenges. (Link)
12. Counsel Health raises $25 Million Series A Led by Andreessen Horowitz and GV to Launch Physician-Supervised AI Front Door for Healthcare Following $11 Million Seed Round Counsel Health’s platform delivers instant, context-aware medical guidance via chat or voice, using AI with physician oversight for diagnosis, prescriptions, or referrals and unlimited follow-up. It reports a 96% resolution rate, rapid response times, and measurable cost savings. Serving 100,000+ members now, it’s expanding to reach millions nationwide. (Link)
13. Faeth Therapeutics raises $25 Million, led by S2G Investments, with Support from KdT Ventures, Khosla Ventures, Future Ventures, Cantos Ventures, Digitalis Ventures, B Capital Group, Avicella Capital, THO Seed Fund and Others Faeth Therapeutics’ funding will support a randomized phase 2 trial of its PIKTOR regimen after an 80% response rate and 11-month median progression-free survival in endometrial cancer. The capital enables insulin control research, expansion into rectal cancer and rare metabolic disorders, and growth of the MetabOS™ precision oncology platform. (Link)
