News Healthcare Deals, Investments & Update Week ending Dec 22nd 2025
- Medline (NASD: MDLN) soars 41% in Nasdaq debut after IPO backed by Blackstone, Carlyle, and Hellman & Friedman, raising $6.26 billion in 2025’s largest offering Medline’s IPO drew strong investor interest, valuing the firm at $46 billion after a 41% stock surge. Generating $977 million in profit on $20.6 billion in revenue, the company’s global manufacturing network limits tariff risks. Its steady, cash-rich model contrasts with typical volatile, high-growth market entrants. (Link)
- Cencora (NYSE: COR) (formerly AmerisourceBergen) to acquire majority stake in OneOncology in $5 billion deal, after already holding a minority position, bolstering community oncology network and specialty distribution strategy The deal combines debt financing and an equity rollover to maintain physician autonomy while integrating OneOncology’s nationwide network within Cencora’s platform. The partnership enhances clinical trials, care coordination, and technology access, supporting community-based cancer care. Analysts see the transaction as a strong vote of confidence in oncology’s growth potential. (Link)
- BioMarin (NASD: BMRN) to acquire Amicus Therapeutics (NASD: FOLD) for $4.8 billion, expanding rare disease portfolio with Galafold and Pombiliti-Opfolda The acquisition strengthens BioMarin’s rare disease pipeline by adding Amicus’ Galafold and Pombiliti-Opfolda therapies and kidney candidate DMX-200. These assets complement BioMarin’s enzyme replacement treatments and Voxzogo, supporting revenue growth and global expansion. Analysts view the deal as a strategic fit, reflected in BioMarin’s post-announcement stock surge. (Link)
- Matt Holt to lead creation of Thoreau, a $30 billion AI‑enabled health‑tech venture combining New Mountain Capital’s Datavant, Swoop, Machinify, Smarter Technologies and Office Ally The deal would combine five healthcare tech companies into one AI-focused platform aimed at cutting medical costs for payers and providers. New Mountain Capital is weighing a structure that returns about 12 billion dollars in cash plus equity and warrants to its investors, exceeding prior portfolio valuations. (Link)
- HCAP Partners invests in Puzzle Healthcare to scale post‑acute care coordination platform across U.S. skilled nursing facilities The investment will accelerate Puzzle Healthcare’s expansion of post-acute care coordination services that track patients for 90 days after skilled nursing stays. Operating in 230 facilities across 15 states, Puzzle uses data-driven workflows to reduce readmissions, lower costs, and safeguard providers from Medicare penalties through improved care continuity. (Link)
- Medtronic plc (NYSE: MDT) and MiniMed move toward Nasdaq listing with S‑1 filing for diabetes business IPO The S‑1 filing initiates Medtronic’s plan to spin off its Diabetes unit as MiniMed, which intends to trade on Nasdaq under “MMED.” The IPO and potential split‑off structure depend on regulatory approval and market conditions. MiniMed will focus on AI‑enabled insulin delivery and continuous glucose monitoring technologies. (Link)
- Philips to acquire SpectraWAVE to advance AI‑enabled intravascular coronary imaging and physiology through HyperVue and X1‑FFR The acquisition integrates SpectraWAVE’s X1‑FFR software, which measures coronary blood flow from angiograms, with its HyperVue imaging platform combining OCT and NIRS to visualize arterial plaque. Philips aims to unify AI-driven imaging and physiology tools to improve stent placement accuracy and standardize coronary disease treatment quality worldwide. (Link)
- HealthStream (NASD: HSTM) acquires MissionCare Collective in deal valued up to $40 million to build largest U.S. caregiver career network The deal brings MissionCare Collective’s 5.2‑million caregiver network and platforms like myCNAjobs and CoachUp Care into HealthStream’s hStream ecosystem. It expands workforce solutions to home health and long‑term care providers, addressing caregiver shortages and aging‑population demands through enhanced recruiting, training, and retention tools supported by cash, stock, and earnout terms. (Link)
- XOMA Royalty (NASDAQ: XOMA) to acquire Generation Bio (NASDAQ: GBIO) gaining exposure to Moderna collaboration and ctLNP nucleic acid delivery platform The transaction gives Generation Bio shareholders cash and contingent value rights linked to cash reserves, lease savings, and potential revenues from the Moderna partnership and ctLNP platform. Executed through a tender offer and merger, the deal has 15% shareholder support and is expected to close by February 2026. (Link)
- Accordion acquires Pinnacle Healthcare Advisors, via its financial sponsors Charlesbank Capital Partners and Motive Partners, to build scaled revenue cycle management platform for health systems and healthcare investors The acquisition merges Pinnacle’s expertise in cash acceleration, AR reduction, and EHR optimization with Accordion’s AI-driven RCM Center of Excellence. The combined platform aims to help health systems tackle margin pressures, payer complexity, and denial rates by improving revenue performance through advanced analytics and integrated operational support. (Link)
- INVO Fertility (NASD: IVF) to acquire Indiana clinic Family Beginnings to expand Midwest fertility footprint after $4.0M private placement The acquisition supports INVO Fertility’s U.S. expansion strategy centered on assisted reproductive technology, including INVOcell-based intravaginal culture. Family Beginnings adds a reputable Indiana clinic with $1.2 million in annual revenue and a full fertility service lineup. The $750,000 deal combines cash and preferred stock, with founder Dr. James Donahue remaining as leader. (Link)
- Enjoin acquires Paediatric Resource Group to expand paediatric and adult CDI, APR‑DRG and physician advisor solutions for U.S. hospitals The acquisition combines Enjoin’s adult DRG assurance capabilities with PRG’s paediatric and neonatal CDI expertise to create a unified, tech-enabled revenue integrity platform. It enhances support for children’s and acute-care hospitals through utilization review and denials management, expanding nationwide CDI services under 3 Boomerang’s strategic healthcare platform. (Link)
- Sentact acquires Performance Health Partners and Vizient Patient Safety Organization to build an integrated, analytics‑driven patient safety and incident reporting platform across U.S. care settings The acquisitions expand Sentact’s patient safety capabilities by integrating Performance Health Partners’ advanced incident management system and the Vizient Patient Safety Organization’s nationwide collaborative. Combined, they enhance data-driven risk analysis, workflow automation, and advisory support to help healthcare providers identify risks, improve safety practices, and elevate clinical outcomes systemwide. (Link)
- Prosperous Health acquires Peninsula Health Center to expand integrated outpatient mental health and addiction services across Palos Verdes and the South Bay The merger creates a comprehensive behavioral health network offering detox, outpatient, and long-term therapy within integrated care plans for addiction and mental illness. Combining Prosperous Health’s physician-led model with Peninsula’s accredited programs enhances local access, continuity of care, telehealth services, and collaboration with hospitals and public health partners. (Link)
Recently Released Industry Report: Longevity Emerging Infrastructure in Preventative Health Dec 2025
Longevity is increasingly capturing attention of investors due to the explosive growth—but what does it truly entail?
In our recently released industry paper “Longevity: The Emerging Infrastructure of Preventative Health,” we examine current market dynamics, distill the complexities into a practical framework, highlighting recent trends, investments and include an optional in-depth exploration of the underlying science.
This industry paper aims to provide investors, analysts, and stakeholders with the essential knowledge to effectively engage with and benefit from this emerging Longevity industry.
Highlights Include:
– What is Healthcare Longevity?
– Market Drivers and Recent Investment Activity
– Key Longevity Sector Discussions:
– Clinical Delivery Models
*Geroscience and Therapeutics
*Precision Diagnostics and Predictive Analytics
*Data & AI Systems
*Psychological and Behavioral Health
*Hormonal and Reproductive Longevity
– Longevity Clinics – A Maturing Market / Emerging Pattern and Investment Opportunity
– Private Equity and Venture Investments
Shore Capital Partners, Boyne Capital, Capitala Group, Platt Park Capital, Panacea Venture, RA Capital Management, BOLD Capital Partners, Khosla Ventures, Gaingels, Longevity Science Foundation, ARCH Venture Partners
News Healthcare Deals, Investments & Update Week ending Dec 15th 2025
- Novo Nordisk completes $4.7B acquisition of Akero Therapeutics (Nasdaq: AKRO) with additional $0.5B CVR tied to EFX approval Akero Therapeutics becomes a wholly owned subsidiary following the acquisition, delisting its shares from Nasdaq. The agreement includes additional payment contingent on FDA approval of EFX for MASH-related cirrhosis. The move strengthens Novo Nordisk’s liver and metabolic disease portfolio and expands its U.S. research and development operations. (Link)
- Teleflex (NYSE: TFX) divests OEM, urology, and acute care units in $2B deals with Montagu, Kohlberg, and Intersurgical Teleflex is restructuring to prioritize its cardiovascular portfolio through divestments totalling $2 billion. Montagu and Kohlberg will acquire its OEM division, while Intersurgical will buy acute care and urology lines. Proceeds will partly fund a $1 billion share repurchase, with both deals expected to close in late 2026. (Link)
- Lumexa Imaging (NASD: LMRI) raises nearly $463M in IPO, earns Moody’s credit upgrade after debt reduction plan The IPO valued Lumexa Imaging at $1.76 billion, with proceeds mainly used to refinance debt and extend maturities, reducing obligations by over $370 million. Moody’s upgraded its rating due to improved credit strength. Founded in 2018, the company operates 184 imaging centers and continues expanding through acquisitions and AI initiatives. (Link)
- Cycle Pharmaceuticals to acquire Applied Therapeutics (Nasdaq: APLT) to advance CNS rare disease treatments through lead drug candidate Govorestat Applied Therapeutics shareholders will receive cash and contingent value rights tied to regulatory and sales milestones under the merger agreement. Cycle will provide up to $8.5 million in bridge funding to support operations until closing. The board unanimously approved the deal, expected to complete in early 2026. (Link)
- HarmonEyes completes acquisition of iFocus Health to expand AI-driven solutions for ADHD treatment The merger integrates iFocus Health’s AI technology into HarmonEyes’ behavioral health platform to advance personalized ADHD care. Combining data analytics and machine learning, the partnership aims to improve diagnosis, treatment, and patient outcomes while expanding evidence-based, AI-driven mental health solutions for broader accessibility and clinical scalability. (Link)
- Handspring Health acquires Joon Care to expand paediatric and adolescent behavioral health services The merger combines Handspring Health’s paediatric care focus with Joon Care’s virtual therapy model to enhance youth mental health services. It expands market reach through Joon’s Washington base and payer ties while integrating technology for improved engagement and outcomes, supporting Handspring’s growth and evidence-based, scalable care model. (Link)
- Perimeter Solutions to acquire Medical Manufacturing Technologies in $685 million cash deal The transaction adds Medical Manufacturing Technologies’ expertise in minimally invasive device production to Perimeter Solutions’ portfolio, aligning with its strategy to invest in high-margin growth sectors. Funded by debt and cash, the deal expands Perimeter’s presence into medical manufacturing and is expected to close in early 2026 pending approval. (Link)
- AMSURG acquires Advanced Center for Surgery to expand into Central Pennsylvania outpatient market The deal adds a 12,500-square-foot surgical center in Altoona with four operating rooms and 17 specialists to AMSURG’s network. Known for outpatient joint replacements, the facility strengthens AMSURG’s Pennsylvania presence and supports its mission to empower independent physicians and expand access to quality, value-based outpatient surgical care. (Link)
- Select Medical acquires Landmark Hospital of Savannah from Landmark Holdings of Florida to expand long-term acute care services The acquisition adds a 50-bed long-term acute care hospital in Savannah to Select Medical’s network, replacing its former local facility. The site now treats medically complex patients needing extended recovery. This expansion strengthens Select Medical’s Southeast presence and supports its nationwide growth in post-acute and rehabilitation services. (Link)
- Mercy Health and Lifepoint Health open new 72-bed Behavioral Hospital in Youngstown to expand mental health and substance abuse care The new 72-bed behavioral hospital provides inpatient care for mental health and substance use disorders, including programs for veterans and first responders. Using evidence-based, trauma-informed methods, it aims to ease ER burdens and improve community support, with inpatient admissions starting in January and outpatient services launching in May. (Link)
News Healthcare Deals, Investments & Update Week ending Dec 8th 2025
- Hims & Hers Health (NYSE: HIMS) to acquire YourBio Health to add patented, pain-free TAP and HALO blood sampling technology to its wellness platform The acquisition will integrate virtually painless microneedle blood collection into a broader direct‑to‑consumer health platform, enabling fast, high‑quality capillary sampling outside traditional clinics. Protected microtechnology around device design, sample handling, and integration supports future test expansion, while incoming scientific and executive leaders will steer development of more user‑friendly diagnostics after the all‑cash deal closes. (Link)
- Overjet acquires Toledo AI startup DentalBee to combine voice-driven documentation with dental imaging in a unified clinical intelligence platform The transaction pairs real-time voice capture of periodontal measurements, notes, and referral details with AI analysis of X‑rays to create fully structured dental records while easing documentation burden for clinicians. It also underscores Northwest Ohio’s emergence as an AI hub, with regional economic development groups credited for helping the startup reach acquisition. (Link)
- Joi + Blokes acquires HerMD to build a nationwide virtual women’s health platform for menopause, sexual health, and hormonal care The merger will expand access to longer virtual consults with hormone and menopause specialists, broader treatment options, and preventive lab support in every state, while adding research participation opportunities. HerMD’s education-first approach will drive new national learning initiatives as the combined platform works to deliver more consistent, empathetic, evidence-based care to underserved midlife women. (Link)
- Lightbeam Health Solutions acquires Syntax Health to integrate value-based contracting and actuarial modelling into its AI-enabled population health platform The acquisition adds a contract‑modelling engine and actuarial talent into a broader value‑based care operating system, allowing payers and providers to rapidly simulate deals, align on assumptions, and project financial results with more confidence. By tying benchmarking and forecasting directly to contract design, the combined platform aims to reduce administrative complexity and refocus attention on population outcomes. (Link)
- Avandra Health acquires DatCard Systems and Sorna Corporation to build a unified global medical imaging and clinical data platform for patient care and research The enlarged platform will connect distribution tools already embedded at thousands of sites with a federated, de‑identified imaging network, making it easier for hospitals to share studies and for life sciences partners to tap high‑value data. By investing in upgrades and support while preserving existing brands, the organization aims to unlock siloed imaging for both care and research. (Link)
- Ciba Health partners with Quikcard to launch personalized, prevention‑first metabolic and chronic care programs for Canadians The partnership brings structured 12‑month programs with dietitian and health‑coach support, personalized plans, and continuous tracking to help members address metabolic risk and chronic conditions through lifestyle change rather than medication alone. Validated outcomes include meaningful HbA1c drops, sharply reduced overall drug use and costs, and GLP‑1 Step Down participants lowering GLP‑1 dependence while losing weight over six months. (Link)
- XRHealth acquires Innerworld to build an immersive, stepped-care XR platform for mental health and rehabilitation The combined platform will pair always‑on, community‑based mental health support—via live events, facilitator‑led groups, and global peer interaction—with existing VR/AR treatments for pain, rehab, PTSD, stress, addiction, and OCD. By adding Innerworld’s founder as chief clinical officer and building on prior XR acquisitions, the company is constructing a stepped‑care, AI‑enhanced XR ecosystem spanning self‑help to clinician‑guided therapy. (Link)
- Cerbo acquires OptiMantra, via its financial sponsors Search Fund Partners, Applied Equity Partners, Manifestations Capital, Hunter Search Capital, Endurance Search Partners, and Red Forest Capital to build AI-powered practice platform for specialty and integrative care The merger creates a single EMR and practice‑management platform for integrative, functional, direct primary care, concierge, behavioral health, and IV/injectable practices, targeting the operational needs of membership‑ and cash‑pay models. Backed by multiple financial sponsors, the combined team will co‑develop AI‑enabled workflows, CRM-driven growth tools, and upgraded payment capabilities while keeping founders engaged and a customer‑first culture intact. (Link)
- BriteLife Recovery acquires Summit Behavioral Health to add intensive outpatient services to its East Coast addiction treatment network The deal extends care into flexible day and evening intensive outpatient programming at the Princeton Junction site, supported by transportation, alumni services, family recovery programming, and enhanced staff training. BriteLife’s broader network across several East Coast states, plus insurance acceptance and scholarships, is intended to make trauma‑informed, relationship‑centered treatment more accessible. (Link)
- CQ Medical acquires Bionix Radiation Therapy business unit to expand global radiotherapy positioning and marking portfolio The acquisition brings additional radiotherapy accessories and a seasoned sales team under the same umbrella, broadening an existing suite of positioning, immobilization, and image‑guided treatment devices used in oncology. CQ Medical plans to absorb the new product lines into its current manufacturing footprint while Bionix redirects attention and investment to its remaining ambulatory care portfolio. (Link)
- Natera (NASD: NTRA) acquires Foresight Diagnostics in up to $450 million deal to expand minimal residual disease cancer testing portfolio The transaction adds ultra‑sensitive PhasED‑Seq assays that can detect lymphoma relapse at very low circulating tumour DNA levels long before standard imaging, alongside a CLIA‑registered lab and lymphoma expertise that deepen the existing MRD offering. It follows settlement of past IP disputes and comes amid strong cancer testing growth but continued net losses. (Link)
- Paradigm Health raises $78 million Series B from ARCH Venture Partners, DFJ Growth, F-Prime, General Catalyst, GV, Lux Capital, Mubadala Capital, and American Cancer Society’s BrightEdge Fund to expand AI-enabled clinical trial infrastructure The platform links biopharma sponsors with 166 provider organizations and 2,100 care sites across 45 states. Automated matching and site-feasibility tools let health systems enrol up to four times faster and reduce clinician burden, while a new design service embeds interventional and pragmatic trials directly into routine workflows and expands into neuroscience, cardiovascular, and metabolic research. (Link)
- Artera raises $65 million from Lead Edge Capital, Jackson Square Ventures, Health Velocity Capital, Heritage Medical Systems, and Summation Health Ventures to scale agentic AI for patient communication The company is using a decade of real‑world communication data to train AI that automates routine scheduling, intake, billing, and messaging across more than 1,000 provider organizations and 2 billion yearly interactions. Its “flow agents” already handle most exchanges without staff, while co‑pilot tools summarize, translate, and surface priority outreach, saving substantial administrative time. (Link)
- Curi Bio raises $10 million Series B led by DreamCIS to scale human iPSC-based preclinical platforms and advanced functional data analysis for drug discovery Curi Bio is expanding a platform that uses high‑purity human iPSC‑derived cells, tissue‑specific 3D biosystems, and rich functional data to predict human drug responses more accurately than animal or 2D models. These assays guide candidate selection and IND decisions across multiple diseases, while partner DreamCIS contributes clinical research and regulatory expertise to boost trial success. (Link)
- Lyric Bio, Inc. raises $6.6 million seed round led by The Venture Collective, with Black Diamond Ventures, Draper Associates, Lucas Venture Group, Meiji Seika Pharma, SOSV, and others to advance donor‑derived therapeutics biomanufacturing Lyric Bio is building ultra‑high‑density 3D bioreactors that mimic human tissue to manufacture donor‑derived therapies at scale, starting with IVIg and SCIg in a $20 billion market. By targeting up to 100x efficiency gains, the team aims to slash costs, cut reliance on human donors, and deliver more consistent, accessible immunoglobulin products. (Link)
News Healthcare Deals, Investments & Update Week ending Dec 1st 2025
- Patient Square Capital completes $2.6 billion take-private acquisition of Premier, Inc (NASD: PINC), paying $28.25 per share in all-cash deal. The deal takes Premier private and keeps its operations focused on powering healthcare improvement through analytics, supply chain offerings, collaboratives, and advisory services. As part of a larger healthcare-focused portfolio, the company is expected to use additional capital and expertise to enhance technology-driven tools that help providers improve outcomes and reduce costs. (Link)
- Bruker Corporation (NASD: BRKR) acquires AST Revolution to advance WAVE and Arc rapid antimicrobial susceptibility testing technologies and expand clinical diagnostics portfolio The deal shifts a revitalized rapid testing platform into a larger diagnostics ecosystem, keeping focus on delivering quicker, clinically actionable antimicrobial susceptibility results. With prior investment having stabilized and advanced the WAVE and Arc systems, the new owner is expected to use its scale, market access, and technical depth to speed adoption in laboratories and hospitals. (Link)
- MDI NetworX acquires Cobalt MedPlans (Clarity Performance Solutions) from Cobalt Health Solutions, a Blue Cross and Blue Shield of Kansas City Subsidiary, to Expand U.S. Payer Services and Deploy InsightPro AI Platform The deal adds 250 U.S. staff and two Kansas delivery centers, lifting the company’s global workforce above 7,500 and growing its domestic operations to four sites. It plans to intensify investment in automation, analytics, and workforce capabilities to deliver scalable, end-to-end payer operations while tightening control of administrative costs. (Link)
- US Fertility partners with L Catterton and Amulet Capital Partners in new co-lead investor structure to expand access to advanced reproductive care across the U.S. The updated ownership structure preserves significant physician ownership while adding growth capital and consumer-health expertise to scale US Fertility’s clinics, labs, and research programs. It supports broader access to IVF, IUI, genetic testing, and related services, while reinforcing a physician-led, patient-centered care model for tens of thousands of new patients annually. (Link)
- MedEdge Holdings launches with $450 million management-led buyout to integrate Abyrx’s biomaterials portfolio and Kairuku’s surgical SaaS platform The holding company will merge biomaterials and surgical software capabilities to streamline product sourcing, inventory control, and case coordination for hospitals and OR teams. Profitable operations plus new capital will fund acquisitions of 10–15 commercial-stage products, aiming to cut administrative complexity while broadening access to next‑generation surgical technologies. (Link)
- FluidAI Medical acquires Emmetros Limited, developer of SparxConnect, to strengthen AI-driven Stream Inara patient engagement The integration focuses on stronger postoperative monitoring and communication, using collaboration tools to guide patients before procedures and through home recovery. It supports earlier discharge while preserving visibility into outcomes and patient‑reported data, and complements existing monitoring, surgical decision support, and recovery programs to boost throughput, bed utilization, and personalized recovery planning. (Link)
- Innova Therapeutics acquires Enci Therapeutics to advance IVT-8086, a first-in-class monoclonal antibody targeting SFRP2 in solid and hematologic cancers The deal centralizes control of IVT-8086 to accelerate its development as a targeted therapy against a key signalling pathway driving angiogenesis, tumour growth, immune evasion, and metastasis. Strong preclinical data support its potential both as monotherapy and in combination with checkpoint inhibitors, alongside a companion diagnostic to guide detection, prognosis, and relapse monitoring. (Link)
- MiCare Path acquires Compwell, LLC to accelerate national expansion of AI-powered virtual care platform The platform now supports large, multispecialty patient panels with reimbursable programs for remote monitoring and ongoing care management. New capital and the Compwell integration will grow clinical services, deepen health system collaborations, and accelerate AI-driven workflow automation, enabling more proactive, personalized virtual care that extends clinician support into patients’ daily lives. (Link)
- Brown’s Medical Imaging and Prestige Medical Imaging merge to expand nationwide, multi-vendor medical imaging service capabilities The merged business broadens nationwide coverage while maintaining a vendor-agnostic service model with strong uptime and response commitments. A 150‑plus engineer field force provides fast remote and onsite support, underpinned by a customer‑first, end‑to‑end service philosophy. Leadership promotions reinforce continuity and position the company for its next phase of growth. (Link)
- AleraCare, backed by Hildred Capital Management, to merge with Pure Healthcare to Form National Platform for Ambulatory Infusion and Specialty Care The merged platform operates 77 infusion centers in 14 states, pairing complex-chronic-care expertise with expanding home and alternate-site services. A unified contracting and technology backbone supports payors, providers, and biopharma with faster therapy starts, better adherence, and AI-enabled scheduling, benefits checks, and real-time outcomes tracking, while maintaining a safety- and compassion-focused culture. (Link)